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KMID : 0378019790220020047
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New Medical Journal
1979 Volume.22 No. 2 p.47 ~ p.54
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Heavy Metal Concentration of Human Blood in Korea
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Abstract
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Economic development of Korea brought rapid progress and expansion of her industries. Accordingly, numbers of workers in industries who have been exposed to hazards responding to the work process are increasing. Heavy metal poisoning is one of the most important group of chronic poisoning mainly by Cd, Zn, Fe, Mg and Cu in Korea. Since there is no curative way so effective, prevention of exposure and early detection of poisoning are the utmost way of controlling the disease. However, it is very hard to clarify the upper limit of those metal concentrations in normal blood among Korean.
With the reasons, the author tried to establish the normal range of those metal concentrations in blood. For the purpose, a total of 100 people who have not dealt with the above metals in their daily working life were selected as samples of the study. From their blood, concentrations of the above metals were measured with atomic absorption spectrophotometer and the results were analysed in accordance with the characteristics of the samples as shown in the followings.
1. Concentrations of the metals in sampled blood by sex are; 0.027±0.018pg/ml of Cd. in male
0.032±0.024 pg/ml of Cd. in female
2.23±1.79 pg/ml of Cu in male
2.74±1.85 pg/ml of Cu in female
403.16±100.34 pg/ml of Fe in male
360.70±116.14 pg/mi of Fe in female
37.54±9.30 pg/ml of Mg in male
32.30±9.79 pg/ml of Mg in female
16.43±15.94 pg/ml of Zn male
13.82±-9.55 pg/ml Zn in female
2. Simple frequency dispersions of each metal concentration in blood in general showed irregular patterns which are usually positively skewed and quite different from normal distribution proved by goodness of fit test (P-value from 0.01 to 0.005), and cumulative lines on log-probability graphs of each metals also did not show one strait line but mixture of a few strait line which are suspicious of dimodal or trimodal patterns of distribution.
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